在小儿腹腔镜胆囊切除术中短时间静脉注射绿色氨酸:可视化和安全性的前性评估
Vojtech Dotlacil1, Eliska Pajerova2, Dagmar Sovadinova2
1Department of Paediatric Surgery, Second Faculty of Medicine, Charles University and Motol University Hospital, Charles University, V Uvalu 84, Praha 5, 150 06, Prague, Czech Republic. vojtech.dotlacil@fnmotol.cz.
Pediatric surgery international
|August 26, 2025
概括
在小儿腹腔镜胆囊切除过程中,短时间内给予印绿色 (ICG) 是安全有效的. 这种方法提供了高质量的成像, 没有并发症, 提高了手术安全.
科学领域:
- 儿童手术
- 手术成像
- 胃肠病学
背景情况:
- 绿色氨酸 (ICG) 光成像有助于小儿腹腔镜胆囊切除术中的胆道可视化.
- 标准的ICG给药方案 (手术前16-24小时) 可能不适用于儿科LC.
- 优化ICG时间对于增强手术内胆道解剖学识别和预防胆道损伤至关重要.
研究的目的:
- 评估短时间内给予绿色氨酸 (ICG) 的安全性和有效性.
- 评估使用静脉注射Verdye®来增强儿科胆道瘤可视化的可行性.
- 确定手术前ICG治疗间隔的缩短是否会影响手术结果或并发症率.
主要方法:
- 预期单中心研究涉及接受静脉注射Verdye®的儿科LC患者.
- 通过使用Likert,HELPFUL和DISTURBED分数进行外肝胆道解剖学的内科评估.
- 数据收集包括ICG时间,手术时间和并发症 (Clavien-Dindo分类).
主要成果:
- 包括11名儿科患者 (64%为女性,年龄中位数为14岁).
- 在手术前,ICG的中位数为225分钟,中位数为0. 34 mg/ kg.
- 获得高质量的胆道可视化 (利克尔特中位数为5),没有ICG相关的或Clavien- Dindo并发症.
结论:
- 短时间内给予ICG是一种安全且可行的方法.
- 这种方法有效地增强了胆道可视化,有助于预防胆道损伤.
- 短间隔的治疗方案耐受良好,并提供高质量的手术内成像.
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