在养中治疗口服急性毒性的方法 暴露于腐烂的饮用水中的杀虫剂液体 (Phenylpyrazole),Fipronil
Zahraa Y Hanoon1, Muhi N Salman1
1Department of Pharmacy, Baghdad College of Medical Sciences, Baghdad, Iraq.
Journal of applied toxicology : JAT
|August 27, 2025
概括
饮用水中的菲普罗尼尔杀虫剂导致子出现神经和胃肠道问题. 有针对性的治疗有效地控制了症状,显示了野生动物保护和鸟类健康战略的潜力.
科学领域:
- 环境毒理学
- 鸟类健康
- 农药的安全性
背景情况:
- 菲普罗尼尔是一种广泛使用的杀虫剂,对鸟类有已知的毒性风险.
- 关于菲普罗尼尔对家 (Columba livia) 的毒性和治疗的数据有限.
研究的目的:
- 通过受污染的饮用水来确定菲普罗尼尔在家中的急性口服毒性.
- 对子中毒的临床干预措施的有效性进行评估.
主要方法:
- 根据经合组织的指导方针,48只子通过饮用水接触到11.3mg/kg的菲普罗尼尔.
- 在14天内对临床症状,体重和组织残留物进行监测.
- 治疗干预包括葡萄糖盐水,糖酸盐和米达佐拉姆.
主要成果:
- 子表现出神经 (震,) 和胃肠道 (腹,吐) 的进展.
- 脑组织中没有显著的Fipronil残留积累与症状严重程度相关.
- 治疗成功缓解了肌肉和神经毒性症状;对照子没有受到影响.
结论:
- 通过受污染的水,fipronil对家用子构成严重的毒性风险.
- 症状治疗有效缓解子中毒.
- 这些发现支持改善针对农药暴露的禽类临床方案和野生动物保护策略.
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