德尔塔中性粒细胞指数和其他标记在输卵管的预后和预测手术不良事件中的作用
Mohammad İbrahim Halilzade1, Emre Erdem Taş2
1Gynecology and Obstetrics Department, University of Health Sciences Ankara City Hospital, Ankara, Turkey.
Medicine
|August 27, 2025
概括
德尔塔中性粒细胞指数 (DNI) 有效预测手术并发症和卵管 (TOA) 患者的预后. 这种炎症标志物在TOA中比其他测试标志物更有价值.
科学领域:
- 妇科医生
- 外科病理学
- 炎症标记物
背景情况:
- 管卵巢 (TOA) 是一种严重的腹部感染,具有显著的死亡率和手术并发症风险.
- 有效的预后标记对于治疗TOA患者和优化手术结果至关重要.
研究的目的:
- 评估三角中性粒细胞指数 (DNI) 和其他炎症标志物的作用,以预测TOA手术患者的预后和不良事件.
- 将DNI的预测值与白细胞计数,中性细胞/淋巴细胞比率 (NLR),血小板/淋巴细胞比率 (PLR) 和C反应蛋白 (CRP) 进行比较.
主要方法:
- 一项涉及69名经过TOA手术的患者的研究.
- 术前实验室参数分析:白细胞计数,NLR,PLR,CRP和DNI.
- 实验室标记与不良事件的相关性:手术内/术后并发症,ICU入院和停留时间. 用于DNI截止值的ROC曲线
主要成果:
- 在手术后出现并发症的患者中,NLR,PLR,DNI和CRP均升高.
- 在患有术后并发症和需要ICU的患者中,DNI显著更高.
- DNI水平与ICU和住院时间有正相关性,显示了预测并发症和ICU需要的具体切断值.
结论:
- 德尔塔中性粒细胞指数 (DNI) 是一个有价值的,非侵入性的标志物,用于预测TOA手术中的不良事件和预后.
- 与WBC,CRP,NLR和PLR相比,DNI对不良事件的预测性能更好.
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