糖尿病,炎症标志物和组织厚度在消毒和无菌部修复手术
Mücahid Osman Yücel1, Raşit Emin Dalaslan1, Sönmez Sağlam1
1Department of Orthopaedics and Traumatology, Faculty of Medicine, Düzce University, Düzce, Turkey.
概括
与无菌病例相比,复查关节整形术 (RHA) 显示炎症标志物更高,手术时间更长. 糖尿病患者感染的风险更大,软组织的厚度下降可能是感染的后果,而不是原因.
科学领域:
- 骨科手术
- 传染性疾病
- 生物材料科学
背景情况:
- 阴道和无菌松动是修复关节整形 (RHA) 的主要原因.
- 与感染相关的修订带来了复杂的诊断和管理挑战.
- 糖尿病 (DM) 是RHA病例中的相关并发症.
研究的目的:
- 为了比较无菌和无菌的RHA病例.
- 分析炎症标志物,DM流行,手术持续时间,输血需要,软组织厚度和死亡率的差异.
- 研究RHA软组织厚度与感染之间的关系.
主要方法:
- 对49名接受RHA治疗的患者进行回顾性研究 (2015-2020年).
- 患者分为无菌 (n=34) 和败血症 (n=15) 组.
- 人口统计数据,并发症,手术前红细胞沉积率 (ESR),C反应蛋白 (CRP),软组织厚度和手术时间的比较.
主要成果:
- 消毒组的ESR和CRP水平显著提高 (p=0. 002, p=0. 001).
- 在败血症组观察到较低的软组织厚度 (p=0. 003),更高的输血需求 (p< 0. 001) 和更长的手术时间 (p< 0. 001).
- 两组死亡率没有显著差异 (p=0. 576).
结论:
- 败血性RHA病例与炎症标志物升高,输血需求增加和手术时间延长有关.
- 糖尿病与RHA患者的感染风险增加有关.
- 感染病例的软组织厚度降低可能是感染的后果,与此前的文献表明这是一个原因.
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