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Updated: Sep 10, 2025

Exosomal miRNA Analysis in Non-small Cell Lung Cancer NSCLC Patients' Plasma Through qPCR: A Feasible Liquid Biopsy Tool
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将SERS映射与可解释的深度学习相结合,用于外体分析,以提高肺癌的检测

Hui Chen1, Luyao Wang1,2, Dandan Fan1

  • 1Key Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, University of Shanghai for Science and Technology, Shanghai, 200093, China. chenhui@usst.edu.cn.

The Analyst
|August 27, 2025
PubMed
概括

本研究使用表面增强的拉曼散射 (SERS) 和深度学习来分析外体生物标志物以改善肺癌检测. 可解释的人工智能模型通过分析表面和内部外体信号实现了98.95%的准确性.

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相关概念视频

Overview of Exosomes01:36

Overview of Exosomes

Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
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