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Updated: Sep 10, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay

Published on: February 9, 2021

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作为具有潜在抗癌活性的创新细胞循环调节剂的混合核基-异环-2-氧基架

Gehan Ahmed Abdel-Hafez1, Dagmara Kłopotowska2, Beata Filip-Psurska2

  • 1Medicinal Chemistry Department, Faculty of Pharmacy, Merit University Sohag Egypt.

RSC advances
|August 27, 2025
PubMed
概括

针对多种癌症途径的新混合分子显示出强大的抗增殖作用. 化合物8b和12a-12c具有显著的CDK6和VEGFR-2抑制作用,其性能优于现有的药物,因此有必要进一步开发癌症治疗方法.

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Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics06:00

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