Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

293
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
293
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

213
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
213
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

23
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
23
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

334
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
334
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

33
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
33
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

38
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
38

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Prognostic value of 9 immune-inflammatory markers for patients with dilated cardiomyopathy: A retrospective study.

International journal of cardiology. Cardiovascular risk and prevention·2026
Same author

Small Dense Low-density Lipoprotein Cholesterol as a Prognostic Risk Factor in Premature Acute Coronary Syndrome with Multivessel Disease: A Retrospective Cohort Study.

Journal of atherosclerosis and thrombosis·2025
Same author

Interaction and biological pathway analysis of proteomic products in patients with premature coronary artery disease.

Clinical proteomics·2025
Same author

Association of small dense low-density lipoprotein cholesterol with cardiovascular risk in premature acute coronary syndrome and multivessel disease: a single-centre retrospective cross-sectional study.

BMJ open·2025
Same author

PCSK9 gene Polymorphism and Assessment of Cardiovascular Risk and Prognosis in Patients With Hyperlipidemia: A Retrospective Cohort Study.

Journal of clinical hypertension (Greenwich, Conn.)·2025
Same author

Dilated cardiomyopathy signature metabolic marker screening: Machine learning and multi-omics analysis.

Heliyon·2025

相关实验视频

Updated: Sep 10, 2025

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
10:03

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Published on: January 28, 2020

5.4K

在冠心病患者中,血清髓氧化酶 (MPO) 度与甘油三糖指数 (TyG) 的预测值为主要心血管不良事件 (MACE).

Adila Wulamu1, Xiao-Lei Li2,3, Munawaer Keremu2

  • 1Emergency Center, First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, Xinjiang, China.

International journal of cardiology. Cardiovascular risk and prevention
|August 27, 2025
PubMed
概括

在冠心病 (CHD) 患者中,高髓氧化酶 (MPO) 和高甘油三糖 (TyG) 指数协同增加主要心血管不良事件 (MACE) 的风险. 结合MPO和TyG指数可以改善心血管风险预测.

关键词:
冠状动脉疾病主要心血管不良事件骨髓氧化酶三糖-葡萄糖指数

更多相关视频

A Sensitive and Specific Quantitation Method for Determination of Serum Cardiac Myosin Binding Protein-C by Electrochemiluminescence Immunoassay
10:12

A Sensitive and Specific Quantitation Method for Determination of Serum Cardiac Myosin Binding Protein-C by Electrochemiluminescence Immunoassay

Published on: August 8, 2013

16.8K
Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
07:29

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein

Published on: October 12, 2017

9.4K

相关实验视频

Last Updated: Sep 10, 2025

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
10:03

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Published on: January 28, 2020

5.4K
A Sensitive and Specific Quantitation Method for Determination of Serum Cardiac Myosin Binding Protein-C by Electrochemiluminescence Immunoassay
10:12

A Sensitive and Specific Quantitation Method for Determination of Serum Cardiac Myosin Binding Protein-C by Electrochemiluminescence Immunoassay

Published on: August 8, 2013

16.8K
Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
07:29

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein

Published on: October 12, 2017

9.4K

科学领域:

  • 心脏病学
  • 生物标志物
  • 风险预测

背景情况:

  • 冠心病 (CHD) 是全球主要的死亡原因.
  • 在心血管疾病患者中,骨髓氧化酶 (MPO) 和甘油三糖 (TyG) 指数的预后值是不确定的.

研究的目的:

  • 研究MPO和TyG指数对心血管重大不良事件 (MACE) 的综合预测值.
  • 评估MPO和TyG指数对MACE风险的独立和协同作用.

主要方法:

  • 分析了731名心血管疾病患者,根据MPO和TyG指数水平的中位数分类.
  • 在出院后两年内对MACE的发生进行后续调查.
  • 使用多变量逻辑回归,卡普兰-梅尔分析和ROC曲线分析.

主要成果:

  • 较高的MPO和TyG指数水平与MACE风险显著增加有关.
  • MPO (OR=1. 01) 和TyG指数 (OR=2. 80) 是MACE的独立预测指标.
  • 综合AUC为0. 71,表明MPO增强了MACE的TyG指数的预测功效.

结论:

  • 在心脏病患者中,MPO和TyG指数在提高MACE风险方面具有协同作用.
  • 同时评估MPO和TyG指数对于对该群体进行全面的心血管风险评估至关重要.