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Updated: Sep 10, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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产前压力会导致 GABA 活性群体的短暂发育变化,并导致长期的行为异常

Keren Shoshani-Haye1,2, Gilgi Friedlander3, Ofra Golani4

  • 1Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot, Israel.

Neurobiology of stress
|August 27, 2025
PubMed
概括

在小鼠中产前压力会导致持续的焦虑和抑郁, 这些行为变化持续到成年期,

关键词:
抑制性神经元中部前额皮层神经发育产前压力与压力相关的行为

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Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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