与单独使用POEM相比,口腔内镜肌肉切除术的安全性和有效性:国际多中心队列研究
Michel Kahaleh1, Vera Hapshy2, Juan A Alcívar3
1Foundation of Interventional and Therapeutic Endoscopy, New York, United States.
Endoscopy international open
|August 27, 2025
概括
与单独使用POEM相比,POEM- F显著改善了口腔内镜肌切除术 (POEM) 后的胃食管反流病 (GERD). 这种内镜基复合技术为GERD患者在POEM后提供了更好的症状控制.
科学领域:
- 胃肠病学
- 手术内镜
- 逆流性疾病的管理
背景情况:
- 胃食道反流 (GERD) 是一个常见的并发症后口腔内镜肌切除术 (POEM) .
- 用内镜进行的POEM (POEM-F) 是治疗POEM后GERD的一个新兴技术.
研究的目的:
- 为了比较POEM- F与单独使用POEM在治疗阿卡拉西亚后治疗GERD的疗效.
- 在接受POEM或POEM- F的患者中评估临床成功,pH监测和症状得分.
主要方法:
- 一项多中心队列研究包括接受POEM或POEM- F的患者.
- 主要结局包括PPI停止/ 减少,百分比时间pH< 4,DeMeester得分和Eckardt得分.
- 二次结果评估了不良事件,手术时间和住院时间.
主要成果:
- 与POEM (24%) 相比,POEM-F显示了明显更高的PPI停止/减少率.
- POEM- F组的时间pH值< 4 (2. 75%与9. 3%) 和DeMeester评分 (9. 6与15. 8) 的比例较低.
- 两组的技术成功率为100%,在6个月的POEM- F中不需要重复干预.
结论:
- 与单独使用POEM相比,POEM-F在治疗POEM后的GERD方面取得了显著的改善.
- 内镜 fundoplication 是一个有效的辅助 POEM 的 GERD 控制.
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