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相关概念视频

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

382
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
382
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

321
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
321
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

540
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
540
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

375
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
375
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

419
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
419
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

189
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
189
这页已由机器翻译。其他页面可能仍然显示为英文。View in English
  1. 首页
  2. 研究领域
  3. 生物医学和临床科学
  4. 心血管医学和血液学
  5. 心脏病 (包括心血管疾病)
  6. 在住院和非住院的炎症性肠病患者中与共患病相关的因素:单中心初步研究

在住院和非住院的炎症性肠病患者中与共患病相关的因素:单中心初步研究

Marco Vincenzo Lenti1,2, Alice Silvia Brera2, Giacomo Broglio1,2

  • 1Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.

Journal of multimorbidity and comorbidity
|August 27, 2025

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Chronic Salmonella Infection Induced Intestinal Fibrosis
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Chronic Salmonella Infection Induced Intestinal Fibrosis

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A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease
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A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease

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Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach
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在PubMed 上查看摘要

概括
此摘要是机器生成的。

在炎症性肠病 (IBD) 中,并发症很常见,影响超过60%的患者. 年龄较大,女性性别和较低的社会经济地位等因素与IBD的并发病率较高有关.

科学领域:

  • 胃肠病学
  • 内部医学
  • 公共卫生

背景情况:

  • 炎症性肠病 (IBD) 经常与并发症有关.
  • 了解IBD的患病率和影响因素对于患者的管理至关重要.

研究的目的:

  • 评估住院和未住院的炎症性肠道疾病 (IBD) 患者的并发病率.
  • 确定与IBD患者的并发症相关的临床和社会经济因素.

主要方法:

  • 一项对住院IBD患者与性别和年龄相匹配的IBD门诊患者 (2:1比) 的比较研究,来自San MAtteo复杂性研究 (SMAC) (2017-2019).
  • 评估并发病率及其与临床和社会经济因素的关联,包括年龄,性别,虚弱,收入,教育和多药性.

主要成果:

  • 在104名IBD患者中,共患病率为60. 6%,住院患者的发病率略高于非住院患者的发病率 (58. 5%).
  • 伴并发症患者年龄较大,疾病严重程度较高 (CIRS评分),女性更常见,身体较脆弱,教育水平较低.
  • 双变量分析确定年龄>65,女性性别,收入<1000欧元,学历<8年,虚弱和多种药物作为伴随性因素.

结论:

  • 在炎症性肠道疾病 (IBD) 患者中存在高患病率.
关键词:
克罗恩病多病态性多种慢性疾病性结肠炎

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Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach
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  • 低社会经济地位和低教育水平可能是IBD并发症负担的重要因素.