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Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

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Updated: May 11, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

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在KEYNOTE-522:病例报告后改善的三重阴性转移性乳腺癌

Edoardo G Frezza1, Gayatri D Nimmagadda2, Olutayo Sogunro3

  • 1Medicine, Trinity School of Medicine, Baltimore, USA.

Cureus
|August 27, 2025
PubMed
概括

转移性乳腺癌 (MpBC) 是一种罕见而侵袭性的亚型,通常会抵抗治疗. 一个三阴性MpBC病例对化疗加上 pembrolizumab 免疫疗法显示出完全的反应,为改善结果提供了希望.

科学领域:

  • 癌症学
  • 免疫疗法
  • 乳腺癌研究

背景情况:

  • 转移性乳腺癌 (MpBC) 是一种罕见的侵袭性亚型,三阴性MpBC (TN- MpBC) 对常规疗法反应不佳.
  • 标准治疗对TN-MpBC的疗效有限,需要新的治疗方法.
关键词:
乳腺癌心脏样症 (cs)主要说明 522转移性转移性乳腺癌三重阴性乳腺癌

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