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Updated: Sep 10, 2025

Delivery of Modified mRNA in a Myocardial Infarction Mouse Model
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用于针对不良心脏重塑的条件siRNA可编程 рибо交换机的开发

Priyanka Gokulnath1, Ane M Salvador1, Caleb Graham2

  • 1Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

Molecular therapy. Nucleic acids
|August 27, 2025
PubMed
概括

研究人员开发了一种新的条件-siRNA (Cond-siRNA),用于针对细胞特异性基因沉默的疾病生物标志物. 这种方法通过沉默心脏细胞中的素素基因有效降低心脏缩, 为心力衰竭提供了有前途的新疗法.

关键词:
MT:氧核酸:治疗方法和应用对于RNA疗法氨酸心脏缩心脏衰竭心脏在芯片上的模型片切换器siRNA 其他组织特异治疗

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