生物造的ZnO纳米颗粒使用Salvia hispanicaL.微绿因其对食源性病原体的潜在抗菌活性
Baru Venkata Naga Sahithi1, Vasantha Veerappa Lakshmaiah1
1Department of Life Sciences, CHRIST (Deemed to be University) Bangalore-560029 India vasantha.vl@christuniversity.in.
RSC advances
|August 27, 2025
概括
使用微绿来制造具有强烈抗菌性能的氧化纳米颗粒 (ZnO NPs). 这些绿色合成的ZnONP显示出对抗食源性病原体的潜力,例如Staphylococcus pasteuri和Aeromonas caviae.
科学领域:
- 纳米技术
- 绿色合成
- 食品科学
背景情况:
- 微绿色含有丰富的生物活性化合物,
- 绿色合成提供了一种使用植物提取物制造纳米粒子的可持续方法.
- 氧化纳米颗粒 (ZnO NPs) 有多种应用,包括抗菌用途.
研究的目的:
- 使用微绿提取物合成和表征ZnONP.
- 研究这些纳米颗粒对食源性病原体的抗菌活性.
- 探索微绿衍生ZnONP作为天然抗菌剂的潜力.
主要方法:
- 绿色合成ZnONP使用西班牙 (Salvia hispanica) 微绿色提取物
- 通过UV-Vis光谱,XRD,FTIR,SEM,DLS和TEM对ZnONP进行表征.
- 在分子对接中,对抗食源性病原体 (空腔菌,粘菌菌).
- 微绿色衍生ZnONP (MG-ZnONP) 的抗菌活性测试 (MIC,MBC).
主要成果:
- 成功合成稳定的ZnONP (79.4纳米大小,-42.2毫伏泽塔电位).
- 在分析中预测了植物化学物质和病原体受体之间的相互作用.
- MG- ZnO NPs表现出显著的抗菌活性,特别是对S.
- S. pasteuri 的MIC值为62.5微克/毫升,A. caviae 的MIC值为250微克/毫升.
结论:
- 微绿提取物对ZnONP的绿色合成是有效的.
- MG- ZnO NPs对通过食物传播的病原体具有强烈的杀菌活性.
- 这些发现表明MG-ZnONP在食品保存和安全方面的应用具有前景.
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