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Updated: Sep 10, 2025

Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration
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Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration

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连续的毛孔大小梯度增强了骨质构架中干细胞的区域特异化

Gioacchino Conoscenti1,2, Kyra W Y Smith3,4, Alessandro Pirosa2

  • 1Department of Civil, Environmental, Aerospace, Materials Engineering, Università degli Studi di Palermo Palermo Italy.

RSC advances
|August 27, 2025
PubMed
概括

这项研究开发了一种具有渐变孔径的聚-l-乳酸支架,用于再生骨质中缺陷. 这种支架成功地支持了软骨和骨细胞的生长,

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Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

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Stem Cell Niche01:26

Stem Cell Niche

The stem cell niche is the dynamic microenvironment where stem cells reside. Inside these niches, the cells may remain undifferentiated, undergo high self-renewal, or become lineage-specific progenitors. Stem cells coexist with other niche cells, such as stromal cells. They also interact closely with the ECM. Cell-cell and cell-matrix communication occur via adhesion molecules or soluble factors that signal the stem cells and determine their fate. Stromal cells also provide survival signals to...
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