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在患有生长和青春期障碍的儿童中,BoneXpert和IB-Lab-PANDA自动骨龄评估的比较

Inge-Lore Ruiz-Arana¹, Victor Lechanteur², Kanetee Busiah¹

¹Pediatric Endocrinology, Diabetes and Obesity Unit, Department Woman-Mother-Child, Lausanne University Hospital, Lausanne 1004, Switzerland.

Journal of the Endocrine Society

|August 27, 2025

概括

人工智能 (AI) 的骨年龄 (BA) 评估工具IB-lab-PANDA®和BoneXpert®的准确性与人类评分器相美. 在青春期前的儿童中,BoneXpert® 显示出更高的准确性,突出了AI

科学领域:

放射学和医学成像
儿童内分泌学
医疗保健中的人工智能

背景情况:

骨质年龄 (BA) 评估对于诊断儿童生长障碍至关重要,但传统上需要时间.
基于人工智能的BA评估工具正在成为有效的替代方案,但它们的比较性能和潜在偏差需要彻底调查.

研究的目的:

将两种商业AI-BA评估系统IB-lab-PANDA®和BoneXpert®的准确性和一致性与手动评估进行比较.
评估AI驱动的BA估计中的潜在年龄,青春期和性别差异.

主要方法:

使用IB-lab-PANDA®和BoneXpert®对2至19岁患者的521张左手X射线图进行分析.
对213张X射线图的子集与格鲁利希-皮尔 (GP) 参考标准进行比较.
精度指标包括平均绝对偏差 (MAD) 和根平均平方误差 (RMSE),分析按性别,年龄,BMI和青春期状态分层.

主要成果:

这两种人工智能方法都显示了人类之间的差异性 (人工智能工具之间的MAD为0.61年).
在青春期前的儿童中,BoneXpert®的准确性明显高于IB- lab- PANDA® (MAD为0. 7与0. 83年,P=0. 027).
与手动评分相比,IB-lab-PANDA®低估了14岁以上女孩的BA (MAD 1. 18岁),两种AI工具都显示了男孩和儿童的BA延迟的积极偏差.

结论:

无论是IB-lab-PANDA®还是BoneXpert®都是准确和高效的BA测定工具,与手工方法相比.
对于青春期前的孩子来说,BoneXpert®似乎更准确.
对IB-lab-PANDA®对青少年女孩的潜在低估意识对于临床应用很重要.

关键词:

准确性人工智能骨头年龄骨健康指数 (BHI)增长的延迟青春期的延迟

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