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富含的草药治疗高甲状腺症的治疗效果:从单个中心进行的一项回顾性队列研究

Yiwen Lai¹, Mengfei Yang², Jing Li³

¹Department of Endocrinology, The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China.

Frontiers in endocrinology

|August 27, 2025

概括

富含的草药 (IRH) 有效治疗格雷夫斯病,改善甲状腺激素水平和抗体标位. 这种传统中医药为抗甲状腺药物提供了一个安全的替代品,具有可比的疗效和持久性.

科学领域:

内分泌学在内分泌学.
传统中国医药传统中国医药
药理学药理学是指药理学的学科.

背景情况:

格雷夫斯病 (GD) 是一种自身免疫性疾病,导致甲状腺功能障碍.
抗甲状腺药物 (ATD) 是一种常见的治疗方法,但正在寻找替代药物.
传统中医 (TCM) 提供了潜在的治疗选择.

研究的目的:

评估富含的草药 (IRH) 的有效性和安全性,作为对Graves甲状腺功能增强症的TCM治疗.
为了比较IRH与传统抗甲状腺药物 (ATD) 的疗效.

主要方法:

追溯队列研究,比较GD的IRH和ATD治疗方法.
倾向性得分匹配 (PSM) 用于平衡患者特征.
逻辑回归,卡普兰-梅尔和考克斯的比例危险模型分析了疗效和影响因素.

主要成果:

在GD患者中,IRH显著改善了血清自由T3 (fT3),自由T4 (fT4),TSH和TRAb水平.
IRH的有效性和持续性与ATD相似,安全性概况相似.
较高的IRH剂量可能会提高疗效,而较年轻的年龄,男性性别,喉和严重的甲状腺毒性可能会降低疗效.

结论:

IRH是一种安全有效的替代疗法,可以治疗轻度至中度的Graves甲状腺功能障碍.
IRH证明了与ATD相比的效果和作用持续时间.
对影响IRH疗效的因素进行进一步的研究是有必要的.

关键词:

中国中国中国中国.严重的甲状腺功能障碍症.队列队列队列队列富含的草药中的.这是一个追溯的回顾.

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