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Alisa Rybkin¹, Victor Lee¹, Melissa R Young¹

¹Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut, USA.

|August 27, 2025

概括

口腔预测分数 (OCCPS) 有效地将口腔癌患者分为风险组,以预测手术后的整体存活率 (OS).

科学领域:

癌症学
癌症研究
临床预测

背景情况:

口腔预测分数 (OCCPS) 是用于预测口腔癌 (OCC) 的远程转移.
它在预测外科治疗OCC的整体存活率 (OS) 中的有用性需要进一步验证.

研究的目的:

评估口腔腔预测得分 (OCCPS) 以预测手术治疗口腔癌 (OCC) 患者的整体存活率.

主要方法:

利用了来自国家癌症数据库 (NCDB) 在2010-2020年间诊断的32317名患者的数据.
根据OCCPS将患者分为标准,中间和高风险组.
采用卡普兰-梅尔分析来比较不同风险组和特定子组的生存状况.

主要成果:

OCCPS将患者分为标准 (51.7%),中间 (22.5%) 和高风险 (25.8%) 组.
五年生存率有显著差异:73. 4% (标准),58. 6% (中等) 和39. 3% (高风险) (p < 0. 001).
该得分有效地分层了阴性边缘,缺少外节延伸 (ENE) 和晚期IVA- B疾病的患者 (p < 0. 001).

结论:

OCCPS是一种已验证的工具,用于将口腔癌患者分为不同的风险类别,以预测整体存活率 (OS).
这种评分系统有助于对接受OCC最终手术的患者进行风险分层.

关键词:

口腔癌的治疗方法预测情况风险建模风险分层状细胞癌

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