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预测新生儿和婴儿持续置换治疗的死亡率和短期结果
Anna Deja1,2, Kamil Deja3,4, Andrea Cappoli5
1Department of Pediatrics and Nephrology, Medical University of Warsaw, Warsaw, Poland.
概括
人工智能模型确定了接受连续置换治疗 (CKRT) 的婴儿和新生儿死亡率和问题的主要因素. 尿量减少和CKRT开始时间延长增加了死亡风险.
科学领域:
- 儿童脏病学
- 危急护理医学
- 医疗保健中的人工智能
背景情况:
- 对于重症新生儿和急性损伤的婴儿,持续的置换疗法 (CKRT) 是至关重要的.
- 在此易受伤害的群体中,确定影响死亡率和不良结局的因素至关重要.
研究的目的:
- 应用人工智能 (AI),特别是XGBoost模型,以确定接受CKRT的新生儿和婴儿的短期结果相关的临床因素.
- 预测该组患者在出院时的死亡率和蛋白尿.
主要方法:
- 使用了EurAKId注册表 (NCT02960867) 的数据,包括使用CKRT治疗的新生儿和婴儿.
- 使用AI XGBoost模型分析临床特征,人类特征和CKRT技术设置.
- 鉴定出出院时死亡率和蛋白尿的主要预测因素.
主要成果:
- 这项研究包括95名患者;整体死亡率为47. 3%.
- 人工智能模型显示尿量较低,血清肌水平较高,CKRT启动延迟,血压较低是死亡风险因素.
- 较高的入院/CKRT开始血清肌和初级病预测出院时的蛋白尿.
结论:
- XGBoost模型有效地识别了儿科CKRT患者的短期结果预测因素.
- 对新生儿和婴儿的死亡风险来说,早期的AKI严重程度和治疗延迟至关重要.
- 主要病和生化标志物是蛋白尿的重要预测因素.
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