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Updated: Sep 10, 2025

Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer
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在基底性乳腺癌中鉴定基因甲基化-miRNA-转录因子输送循环的表观遗传调节网络

Larissa M Okano1, Alexandre L K de Azevedo2, Tamyres M Carvalho2

  • 1Research Institute Pelé Pequeno Príncipe, Faculdades Pequeno Príncipe, Curitiba 80250-060, PR, Brazil.

Cells
|August 27, 2025
PubMed
概括

这项研究揭示了包括DNA甲基化和microRNA在内的表观遗传变化如何在基础性乳腺癌 (BLBC) 中创建复杂的调节网络. 这些发现突显了前循环 (FFL) 作为BLBC进展的关键驱动因素,提供了潜在的治疗点.

关键词:
DNA 甲基化基底类乳腺癌远端探针输送循环这些基因微型RNA监管表观遗传网络转录因子

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