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基质硬度调节高性胆固醇细胞逆转和胆固醇体现型恢复

Da-Long Dong1,2, Guang-Zhen Jin1,3

  • 1Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan 31116, Republic of Korea.

Cells
|August 27, 2025
PubMed
概括

矩阵硬度通过影响状细胞的行为影响了骨关节炎的进展. 软基质促进状细胞表型逆转,为软骨再生和关节炎干预提供了潜在的策略.

关键词:
一个PDMS标志性信号YAP信号提供软骨的再生冠状细胞增大矩阵的刚性机械微环境表型逆转组织工程

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Chromatin modification alters gene expression; therefore, scientists can add histone-modifying enzymes, histone variants, and chromatin remodeling complexes to somatic cells to aid reprogramming into pluripotent stem (iPS) cells.
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