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Updated: Jun 7, 2026

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通过纤维细胞衍生的细胞外囊 (EV) 进行免疫调节

Afsara Tasnim1, Diego Jacho1, Agustin Rabino2

  • 1Department of Bioengineering, University of Toledo, Toledo, OH 43606, USA.

Biomimetics (Basel, Switzerland)
|August 27, 2025
PubMed
概括

可注射支架中的人体纤维细胞外囊 (EV) 重新编程巨细胞以减少炎症并保持组织工程支架的完整性. 这种无细胞的方法增强了再生医学的潜力.

关键词:
原蛋白细胞外囊泡纤维细胞免疫调节炎症的发生巨细胞聚卡普罗拉克组织再生

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Type IV Collagen of Basal Lamina01:05

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Type IV collagen is a 400 nm long, network-forming collagen that acts as a barrier between the epithelial and endothelial cells. Type IV collagen  forms the backbone of the basement membrane by scaffolding with laminin, entactin, proteoglycans, and fibronectin. Apart from rendering structural support to the basement membrane, it also helps entail signaling potentials necessary for both pathological and physiological functions.
A type IV collagen molecule has six alpha chains which can exist in...