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开发用于医学诊断和环境监测的无细胞蛋白质合成生物传感器的最新进展

Tyler P Green1, Joseph P Talley1, Bradley C Bundy1

  • 1Department of Chemical Engineering, Brigham Young University, Provo, UT 84602, USA.

Biosensors
|August 27, 2025
PubMed
概括

无细胞生物传感器通过利用活细胞之外的细胞机械提供环境和医疗用途的敏感检测. 合成生物学和材料科学的进步正在扩大它们的应用,尽管成本和标准化的挑战仍然存在.

关键词:
生物传感器无细胞蛋白质合成环境监测溶解化医疗诊断多重传感基于纸张的检测在护理场所进行测试合成生物学

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Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
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