石墨烯在牙科中的抗菌作用:一个范围审查
Ricardo Martuci1, Susana João Oliveira1, Mateus Martuci2
1Faculdade de Medicina Dentária, Universidade do Porto, Rua Dr. Manuel Pereira da Silva, 4200-393 Porto, Portugal.
Dentistry journal
|August 27, 2025
概括
石墨烯在牙科生物材料中显示出抗菌潜力,但需要对其安全性和标准化使用进行更多研究. 石墨烯氧化物对各种细菌和真菌有效.
科学领域:
- 生物材料科学
- 纳米技术
- 牙科研究
背景情况:
- 在牙科生物材料中的石墨烯功能化提供了抗菌益处.
- 关于石墨烯的毒性,生物相容性和标准化牙科应用的数据有限.
- 石墨烯纳米板块,石墨烯氧化物和减少的石墨烯氧化物是研究的主要形式.
研究的目的:
- 对牙科生物材料中的石墨烯进行现有研究.
- 综合了石墨烯抗菌功效的证据.
- 描述石墨烯功能化牙科生物材料的生物反应.
主要方法:
- 在Clarivate,PubMed和Scopus中使用电子搜索进行范围审查.
- 关键词包括"石墨烯"",抗菌作用"",杀菌作用"和与牙科相关的术语.
- 在查和资格评估中遵循PRISMA-ScR指南.
主要成果:
- 从最初的793篇文章中,包括了21篇研究.
- 石墨烯氧化物对关键的口腔病原体 (例如S. mutans,E. faecalis) 和C. albicans具有显著的抗菌功效.
- 生物相容性和细胞毒性数据相互矛盾,需要进一步调查.
结论:
- 石墨烯作为牙科生物材料的抗菌剂具有前景.
- 为了澄清生物相容性和细胞毒性,需要进行进一步的体外和体内研究.
- 牙科应用需要标准化的协议,临床指南和监管框架.
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