在近4000名参与者中实施和遵守定制移动应用程序:从长线RisCoin研究中的见解
Ana Zhelyazkova1, Sibylle Koletzko2,3, Kristina Adorjan4,5
1Institut für Notfallmedizin und Medizinmanagement (INM), LMU Klinikum, LMU München, 80336 Munich, Germany.
Infectious disease reports
|August 27, 2025
概括
RisCoin研究的移动应用程序改善了医疗保健工作者和炎症性肠道疾病患者的COVID-19疫苗接种失败风险因素的数据收集. 根据人口统计和健康因素而有所不同,这突出了实施方面的考虑.
科学领域:
- 临床研究
- 数字健康
- 流行病学
背景情况:
- 这项长度RisCoin研究研究了医疗保健工作者 (HCW) 和炎症性肠道疾病 (IBD) 患者的COVID-19疫苗接种失败风险因素.
- 一个定制的移动应用程序用于研究队列内的安全数据收集和通信.
研究的目的:
- 评估研究的移动应用程序的实施,遵守,好处和局限性.
- 评估应用程序在管理临床研究队列和收集纵向数据方面的实用性.
主要方法:
- 一个定制的移动应用程序促进了安全的数据收集,结果传播和通信.
- 参与者应用程序的使用 (下载,登录,提交) 从2021年10月至2022年12月进行了跟踪.
- 多变量逻辑回归确定了与应用程序坚持相关的因素.
主要成果:
- 91%的参与者使用该应用程序,其中28%被确定为坚持使用者 (≥12个提交).
- 随着年龄的增长,应用程序的坚持与特定的HCW角色,流感疫苗接种和非吸烟状态有关.
- 暴露于SARS-CoV-2的IBD患者和报告疫苗不良事件的患者表现出更高的坚持.
结论:
- 该应用程序为队列管理和纵向数据收集提供了一个安全的平台, 提高了参与者的参与度.
- 应用程序的可用性,技术挑战和参与者特征对于优化临床研究的坚持至关重要.
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