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具有双重伤痕抑制和抗菌性能的功能性压缩织物:微封装设计和性能评估

Lihuan Zhao^1,2, Changjing Li¹, Mingzhu Yuan¹

¹School of Textile Science and Engineering, Tiangong University, Tianjin 300387, China.

Journal of functional biomaterials

|August 27, 2025

概括

这项研究开发了一种新的压缩服装织物 (CGF),其中嵌入了聚二甲基 (PDMS) 微囊. 增强的CGF提供了更好的抗菌特性和痕增生抑制,解决了传统的压疗法的局限性.

科学领域:

生物材料科学
织工程
皮肤病学

背景情况:

传统的伤增生压力疗法使用和压缩服 (CGs).
限制包括细菌感染,卫生问题以及由于复杂的应用而减少CG的寿命.
需要具有痕治疗和抗菌功能的先进的CG.

研究的目的:

开发一种具有痕增生抑制和抗菌特性的新型压缩服装织物 (CGF).
克服与传统的基压力疗法相关的局限性
通过改善痕治疗材料来提高患者的服从性和生活质量.

主要方法:

使用素四级盐 (HACC) 和藻酸盐 (SA) 合成了装有多甲基 (PDMS) 的微囊 (PDMS- M).
使用PDMS-M对CGF进行了修改,随后使用 (3-aminopropyl) triethoxysilane (APTES) 进行了修改,然后使用HACC进行进一步处理.
包括X射线光电子光谱 (XPS) 和富里埃变换红外光谱 (FTIR) 的表征;评估了抗菌活性和洗耐用性.

主要成果:

修改后的CGF表现出显著的抗菌率:94. 2%对大肠杆菌 (大肠杆菌) 和83. 1%对金黄色葡萄球菌 (金黄色葡萄球菌).
PDMS- M- HACC CGF 对两种细菌的抗菌率达到了99. 9%,具有优异的洗耐用性 (大肠杆菌的AA级,黄金杆菌的A级).
完成的CGF保持了良好的生物相容性和透性,弹性回收,空气透性和柔软性略有降低.

结论:

开发的PDMS-M-HACCCGF有效地整合了痕增生抑制和强大的抗菌功能.
这种新的织物为传统方法提供了有前途的替代方案,
通过提供更方便和有效的痕管理解决方案, 预计增强的CGF将改善患者的生活质量.

关键词:

抗菌性能基托桑四级盐压缩服装面料微囊聚二甲基甲基酸盐

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