根茎蔬菜的农药风险的优先级和敏感性
Milica Lučić1, Antonije Onjia2
1Innovation Center of the Faculty of Technology and Metallurgy, 11120 Belgrade, Serbia.
Journal of xenobiotics
|August 27, 2025
概括
在塞尔维亚的蔬菜中发现了农药残留物, 虽然风险一般较低,但儿童对饮食累积暴露的敏感性更高,特别是生和菜.
科学领域:
- 食品安全分析
- 环境毒理学
- 公共卫生营养
背景情况:
- 食品中的农药残留物可能会对健康造成危害.
- 蔬菜是通过饮食接触农药的主要来源.
- 评估累积的农药暴露对于准确的风险评估至关重要.
研究的目的:
- 调查塞尔维亚常用蔬菜中的农药残留物.
- 评估与成人和儿童接触农药相关的急性和慢性饮食风险.
- 确定对饮食风险贡献最大的特定蔬菜.
主要方法:
- 使用高性能液体染色学-双重质谱法 (HPLC-MS/MS) 和气体染色学-质谱法 (GC-MS/MS) 分析了580个蔬菜样本.
- 检测出33种不同的农药残留物.
- 计算危险系数 (HQ),危险指数 (HI) 和急性参考剂量 (ARfD) 和可接受每日摄入量 (ADI) 的百分比.
- 应用蒙特卡洛模拟用于慢性暴露的变化.
主要成果:
- 在580个样本中检测到33种农药;29个样本超过了最大残留量 (MRL).
- 儿童的累积急性风险达到了63. 1%,成人为51.1%,生和菜是高风险物品.
- 慢性风险仍然低于安全值 (HI < 1),但儿童的敏感性更高 (11. 0% ADI).
- 敏感性分析强调体重和消费率是关键的风险因素.
结论:
- 虽然塞尔维亚蔬菜中农药的总体风险在可以接受的范围内,
- 由于它们对累积急性风险的贡献,需要特别注意生和菜.
- 监测和风险管理策略应考虑特定人群的消费模式和易感性.
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