无症状个体的晚期加多增强变化:与扩张性心肌病的比较
Seoyeon Park1, Soo Jin Cho2, Sung Mok Kim3,4
1School of Medicine, Sungkyunkwan University, 2066, Seobu-ro, Jangan-gu, Suwon-si 16419, Republic of Korea.
Journal of cardiovascular development and disease
|August 27, 2025
概括
在无症状个体中, septal 条纹是一种晚期 gadolinium 增强 (LGE). 虽然LGE的范围和厚度在无症状患者和扩张性心肌病 (DCM) 患者之间有所不同,但正常的LGE不应被误认为是疾病.
科学领域:
- 心脏病学
- 放射学
- 医学成像
背景情况:
- 在无症状个体中,心脏MRI上的晚期加多增强 (LGE) 可能以隔膜条纹的形式出现.
- 这些发现可以模仿扩大心肌病 (DCM) 患者的异常LGE.
研究的目的:
- 评估无症状个体的LGE变异的频率和程度.
- 在无症状患者和DCM患者之间比较LGE特征.
主要方法:
- 对273名无症状患者和100名DCM患者的心脏MRI扫描进行了回顾性分析.
- LGE定义为心肌信号强度大于正常值的5个标准偏差.
- 在右心室插入点 (RVIP) 和中心室隔膜中进行LGE评估.
主要成果:
- 在99. 3%的无症状患者和100%的DCM患者中观察到LGE.
- 两组之间心肌段数量 (LGE5. 5与7. 6) 和LGE厚度 (4. 5mm与5. 7mm;RVIPs:6. 1至6. 4mm与8. 7至8. 6mm) 的显著差异 (p<0. 001).
- 尽管具有不同的特点,但LGE模式存在相当大的重叠.
结论:
- 与DCM相比, Septal条纹在无症状个体中很常见,并表现出不同的LGE特征.
- 在心肌疾病评估中,正常的LGE发现不应被误解为病态.
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