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在COXPD8中功能障碍的电子传输链组件

Gisela Beutner1, Heidie L Huyck2, Gail Deutsch3

  • 1Department of Pediatrics-Division Cardiology, University of Rochester Medical Center, Rochester, NY 14642, USA.

Journal of cardiovascular development and disease
|August 27, 2025
PubMed
概括

由AARS2基因突变引起的组合氧化酸化缺陷8型 (COXPD8) 会导致严重的婴儿疾病. 这些突变损害了电子运输链的复杂组合和超级复杂的形成,导致生物能量压力.

关键词:
其他:电子输送链缩性心肌病症线粒体疾病线粒体超级复合体

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