在口腔炎患者中与衰老和唾液功能下降相关的口腔候群
Yeon-Hee Lee1,2, Solsol Seo1, Tae-Seok Kim1
1Department of Orofacial Pain and Oral Medicine, Kyung Hee University, Kyung Hee University Dental Hospital, #613 Hoegi-dong, Dongdaemun-gu, Seoul 02447, Republic of Korea.
Journal of fungi (Basel, Switzerland)
|August 27, 2025
概括
减少的唾液流,一种称为异口症的情况,是口腔候群病患者的重要预测因素. 这种真菌感染与未经刺激的唾液流量减少的关系比与单独的年龄有关.
科学领域:
- 口腔医学
- 传染性疾病
背景情况:
- 口腔炎涉及口腔粘膜炎症,口腔角膜炎是一种常见的真菌感染亚型.
- 在口腔炎患者中经常观察到唾液流量减少 (口),可能会增加对真菌感染的易感性.
研究的目的:
- 在口腔炎患者中研究口腔候群病与唾液流量减少之间的关联.
- 在这一群体中确定口腔角膜炎的临床预测因子.
主要方法:
- 通过Candida albicans培养物对259名口腔炎患者进行了评估.
- 测量非刺激的唾液流量 (UFR) 和刺激的唾液流量 (SFR),以评估异口症.
- 在Candida阳性和Candida阴性组之间比较临床特征.
主要成果:
- 在31. 3%的患者中诊断出口腔候群.
- 阳性Candida患者年龄较大,UFR和SFR明显较低.
- 减少的UFR是口腔候群的强有力的预测因子 (AUC=0. 658),而异位是通用线性模型中的显著预测因子.
结论:
- 在口腔炎患者中,口腔候群与未受刺激的唾液流量减少的关系比与晚年有关.
- 减少UFR是一个有价值的临床指标,用于预测口腔角膜炎,特别是在老年人中.
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