揭示临床研究护理的专业格局:使用数据挖掘方法进行范围审查
Mattia Bozzetti1, Monica Guberti2, Alessio Lo Cascio3
1Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Nursing reports (Pavia, Italy)
|August 27, 2025
概括
临床研究护士 (CRN) 在临床试验中至关重要, 但面临角色认可和职业发展等挑战. 需要更多的支持和结果数据来加强它们的整合和影响.
科学领域:
- 临床研究护理
- 医疗保健专业人员的角色
- 临床试验管理
背景情况:
- 由于临床试验的复杂性越来越大,临床研究护士 (CRN) 的角色在过去30年里发生了显著的变化.
- CRN已经从以任务为导向的支持转变为包括患者倡导,协议完整性和道德监督在内的角色.
研究的目的:
- 在过去的30年里,
- 检查CRN角色是如何定义,实施和评估的.
- 确定临床研究中影响CRN的关键主题和系统障碍.
主要方法:
- 使用JBI方法和PRISMA-ScR指导方针进行综合范围审查.
- 在主要数据库中搜索了1990-2024年的同行评审和灰色文献.
- 使用主题建模,多重对应分析和k-means集群进行数据分析.
主要成果:
- 四个主要主题出现:临床试验管理,角色感知/团队整合,专业能力/发展以及系统性障碍.
- 他们面临不一致的角色认可,不稳定的合同,有限的职业道路和专业的孤立.
- 由于没有研究报告与CRN作用相关的患者水平结果,存在重大差距.
结论:
- 在临床研究中,CRN发挥着至关重要的,但被低估的作用.
- 结构性挑战阻碍了CRN的发展,可见性和融入研究基础设施.
- 加强机构支持和基于结果的证据生成对于推进CRN的作用至关重要.
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