在怀孕期间评估非处方药物的准确性和安全性:描述性比较研究
Bernadette Cornelison1, David R Axon1, Bryan Abbott1
1R. Ken Coit College of Pharmacy, University of Arizona, 1295 N. Martin Ave., Tucson, AZ 85721, USA.
像ChatGPT-3.5这样的人工智能 (AI) 聊天机器人对于寻求非处方药 (OTC) 建议的孕妇患者来说具有高准确性和完整性. 然而,发现了关键的安全错误,使人工智能成为不安全的独立资源.
科学领域:
- 医疗信息学
- 医疗保健中的人工智能
- 生殖健康
背景情况:
- 孕妇越来越多地使用人工智能获取健康信息,包括非处方药的指导.
- 怀孕期间的药物安全性至关重要,但数据往往有限.
- 人工智能聊天机器人可能提供可访问的信息,但需要严格的安全验证.
研究的目的:
- 评估ChatGPT-3.5在为孕妇提供非处方药物的准确性,完整性和安全性.
- 将人工智能产生的反应与可靠的医疗资源UpToDate®进行比较.
主要方法:
- 一项前性描述性研究评估了药剂师推的87种OTC药物.
- 独立评审者使用5点的利克特级别将ChatGPT-3.5的反应与UpToDate®信息进行了比较.
- 在小组讨论后,建立了共识评级,第三名调查员提供了最终分数.
主要成果:
- 对于正确性 (5/5) 和安全性 (5/5),ChatGPT-3.5获得了高的中位数.
- 完整性获得了4/5的中位数.
- 尽管得分很高,9%的评估 (n=8) 包含安全错误,包括可能导致严重并发症的遗漏.
结论:
- 虽然ChatGPT-3.5在怀孕期间OTC药物信息的准确性和完整性方面表现出强的表现,但安全性问题仍然存在.
- 发现的安全错误,特别是遗漏,使聊天机器人成为孕妇不安全的独立资源.
- 在AI聊天机器人可靠地用于怀孕期间的药物建议之前, 需要进一步的开发和验证.
更多相关视频
05:33Author Spotlight: Alleviating Nausea and Vomiting in Pregnancy with Safe and Effective Auricular Acupuncture
Published on: August 4, 2023
13:35A Convenient Method for Extraction and Analysis with High-Pressure Liquid Chromatography of Catecholamine Neurotransmitters and Their Metabolites
Published on: March 1, 2018
相关概念视频
Teratogenicity
Drug Dosage Regimen: Overview
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Factors Affecting Drug Response: Overview
Drug Administration and Therapy Phases: Overview
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
