西墨西哥青少年代谢综合征的流行及其组成部分
Diego Ortega-Pacheco1, Roberto Carlos Rosales-Gómez2, Teresa Arcelia García-Cobián1
1Instituto de Terapeutica Experimental y Clínica, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara C.P. 44340, Jalisco, Mexico.
Pediatric reports
|August 27, 2025
概括
代谢综合征 (MetS) 影响了17. 2%的青少年,肥胖是主要的危险因素. 主要预测因素包括男性性别,青春期早期,高腰与身高的比率,体脂增加和胰岛素抵抗 (IR).
科学领域:
- 儿童内分泌学
- 代谢健康
- 青少年的健康
背景情况:
- 代谢综合征 (MetS) 在全球青少年中越来越令人担忧.
- 早期识别风险因素对于预防长期心血管和代谢并发症至关重要.
- 西墨西哥的青少年具有独特的人口和健康状况,
研究的目的:
- 在墨西哥西部青少年中确定MetS的患病率.
- 确定与MetS相关的预测性风险因素.
- 探索特定性别的风险因素.
主要方法:
- 一项涉及516名青少年的分析性横截研究.
- 收集人体测量数据,血压和生化标志物.
- 基于德·费兰蒂标准 (2004年) 诊断甲状腺瘤;计算胰岛素耐药性 (IR) 的甘油三指数 (TyG指数);进行后勤回归分析.
主要成果:
- 肥胖青少年中有50%患有这种疾病.
- 腹部肥胖和脂质失调是最常见的MetS组成部分.
- 预测MetS的因素包括男性性别,青春期早期,腰与身高的比率 (WHtR) > 0. 5,增加的体脂百分比,和TyG指数> 4. 68 (IR).
结论:
- 在10名青少年中,有2名患有MetS,男孩的患病率更高.
- 在青少年中,腹部肥胖,低脂蛋白血症,IR和MetS是普遍存在的.
- 患有腹部肥胖,高体脂和IR (TyG指数> 4. 68) 的青少年有更高的MetS风险.
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