热浪和寒流与细颗粒物对肺炎死亡率的相互影响
Yi Zheng1, Ruijun Xu1, Yuling Chen1,2
1Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Toxics
|August 27, 2025
概括
极端温度事件 (ETE) 和细颗粒物 (PM2.5) 会增加肺炎死亡. 热浪和PM2.5的同时暴露会增加风险,而寒冷则会降低风险.
科学领域:
- 环境流行病学
- 公共卫生
- 毒理学
背景情况:
- 极端温度事件和环境细颗粒物 (PM2.5) 与肺炎死亡率的增加有关.
- 对于ETE和PM2.5对肺炎死亡率的相互作用影响尚不清楚.
研究的目的:
- 调查热浪,寒冷和PM2.5对肺炎死亡率的独立和互动影响.
- 量化对ETE和PM2.5的同时暴露导致的肺炎死亡风险.
主要方法:
- 使用了时间分层的病例交叉设计,分析了中国江苏省的50,196例肺炎死亡病例 (2015-2022年).
- 使用经过验证的网格数据集评估了个人对热浪,寒流和PM2.5的暴露.
- 使用与分布式滞后非线性模型集成的条件后勤回归模型来估计影响.
主要成果:
- 热浪和寒冷,以及PM2.5都与肺炎死亡率的增加有关.
- 对热浪和PM2.5的同时暴露观察到一个协同效应 (RERI:0. 401. 16).
- 发现对寒冷和PM2.5的同时暴露具有对抗作用 (RERI: - 1. 02 - 0. 20).
结论:
- 热浪和寒流与PM2.5的相互作用不同,影响肺炎死亡风险.
- 同时暴露于热浪和PM2.5显著增加了肺炎死亡风险.
- 减少对热浪和PM2.5的同时暴露对于减轻肺炎死亡率至关重要.
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