相关实验视频

Updated: May 6, 2026

Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.

Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.

Published on: February 15, 2019

在体外评估中,通过乳杆菌,Pediococcus和Bacillus菌株进行Aflatoxin B1排毒

Sarra Rafai¹, Ana Moreno¹, Alessandra Cimbalo¹

¹Biotech Agrifood Lab, Faculty of Pharmacy and Food Sciences, University of Valencia, Avda. Vicent Andrés Estellés s/n, 46100 Burjassot, València, Spain.

|August 27, 2025

概括

某些细菌菌株,包括乳杆菌,Pediococcus和Bacillus,有望在食物中生物排毒亚毒素B1 (AFB1). 这些微生物有效地降低了AFB1水平,为减轻菌根毒素暴露提供了一种自然方法.

科学领域:

食品科学
微生物学
毒理学

背景情况:

亚毒素B1 (AFB1) 是一种在食品中发现的高度有毒和持久的真菌毒素.
传统的解毒方法有其局限性,

研究的目的:

评估Lactobacillus,Pediococcus和Bacillus细菌菌株在AFB1排毒方面的潜力.
通过先进的分析技术来评估AFB1的减少率和代谢物概况.

主要方法:

细菌菌株 (10 Lactobacillus/Pediococcus, 10 Bacillus) 用受 AFB1 污染的玉米面粉提取物进行化.
使用液体染色学四极飞行时间质谱法 (LC-QTOF-MS) 测量了12小时,24小时和48小时的解毒.
在体外消化模型中模拟了胃肠道条件,以评估解毒效果.

主要成果:

在48小时后,Lactobacillus curvatus14和Pediococcus pentosaceus4显示出显著的AFB1减少.
在24小时后,Bacillus firmus 6显著排毒.
在体外消化模型中发现了大量的AFB1减少,特别是在结肠阶段,P. pentosaceus 4和L. curvatus 14实现了超过69%的减少.

结论:

乳杆菌,Pediococcus和Bacillus菌株具有显著的AFB1生物解毒潜力.
这些发现支持在食品安全策略中使用精选的细菌菌株来减少饮食中的AFB1暴露.

关键词:

生物排毒在体外消化乳酸细菌 (LAB) 的使用菌类毒素

更多相关视频

The Cultivation, Growth, and Viability of Lactic Acid Bacteria: A Quality Control Perspective

The Cultivation, Growth, and Viability of Lactic Acid Bacteria: A Quality Control Perspective

Published on: June 16, 2022

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials

Published on: May 16, 2022

相关概念视频

Production of Organic Acids

Production of Organic Acids

Lactic acid, an important organic acid extensively applied in food, pharmaceutical, and biodegradable polymer industries, is primarily produced via microbial fermentation. This method is favored over chemical synthesis due to its environmental sustainability and capacity for enantiomerically pure product formation. Among various microbial processes, the fermentation of starch-based substrates stands out due to the abundance and renewability of raw materials like corn and potatoes.Hydrolysis of...