儿童重症血液学瘤学外体生命支持的转诊途径:标准化评估和转移可以改善生存率
在PubMed上查看摘要
概括
此摘要是机器生成的。实施关键血液瘤转诊途径 (CHORPE) 改善了需要ECLS的儿科患者的生存率. 这种标准化的方法改善了患者的治疗结果,并减少了转移期间的并发症.
科学领域
- 儿童重症监护医疗
- 血液学-瘤学
- 身体外生命支持
背景情况
- 在血液/瘤患者中,体外生命支持 (ECLS) 的使用正在增加.
- 在该群体中,ECLS的结果稳步改善.
- 需要标准化的评估和转移协议.
研究的目的
- 开发和评估外体生命支持的临床血液瘤转诊途径 (CHORPE).
- 标准化ECLS候选人的早期评估和识别.
- 评估CHORPE对患者结果和转移并发症的影响.
主要方法
- 为ECLS评估转移的患者的回顾性图表审查.
- 在CHORPE之前和之后的实施小组之间的结果比较.
- 分析ECLS的位置,生存率和转移并发症.
主要成果
- 在CHORPE后的组显示显著改善了脱管的存活率 (OR=24, p=0. 01) 和出院率 (OR=15. 9, p=0. 03).
- 在CHORPE后组中,转移期间的并发症较少 (p=0. 0228).
- 临床改善导致使用后需要ECLS的患者减少 (p=0. 0120).
结论
- 标准化的ECLS候选评价方法提高了生存率.
- 早期识别和安全转移与持续护理至关重要.
- 对于患有ECLS的儿童血液瘤患者来说,CHORPE的实施与更好的结果有关.
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