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Updated: Sep 10, 2025

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AIRPred:深度学习模型预测强度比在交叉连接质谱学中改善了交叉连接频谱匹配

Zehong Zhang1,2, Mei Wu1, Max Ruwolt1

  • 1Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin 13125, Germany.

Analytical chemistry
|August 27, 2025
PubMed
概括

通过分析碎片离子强度比,AIRPred是一种深度学习模型,可以改善结构蛋白质学中的交叉连接频谱匹配识别. 这种方法提高了交联质谱 (XL-MS) 分析的准确性.

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Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
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