通过电阻断层扫描在灵活支气管检查中评估肺透气:一项前性试点研究
Yang Gu1, Xiaowei Zhang1,2, Xiang Li1,3
1Department of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, 507 Zhengmin Road, Shanghai, 200043, China.
在支气管镜检查过程中,超旋喷气通风 (SJV) 没有防止肺通风和氧化率下降,但维持了足够的 SpO2. 术前SJV改善了这些指标,与鼻喷气氧化相比,将通风转移到腹部.
科学领域:
- 呼吸系统医学
- 肺病学
- 关键的护理
背景情况:
- 在灵活的支气管镜检查过程中,使用超支气管透气 (SJV) 来增强氧化.
- 它对整体肺透气的影响尚不清楚.
- 胸部电阻断层扫描 (EIT) 提供实时呼吸监测.
研究的目的:
- 使用EIT评估SJV在灵活支气管镜检查期间对肺透气和氧化的影响.
- 为了比较透气分布与SJV与微鼻喷气 (WNJ) 氧化.
主要方法:
- 一项前性试点研究,涉及接受灵活支气管镜检查的患者.
- 胸部EIT在不同时间点测量了末端呼气阻抗 (EELI) 的变化.
- 主要结局:SJV (T2) 期间的 ΔEELI 与支气管检查 (T3) 期间的 ΔEELI. 二次结局包括SPO2和通风分布 (ROIventral).
主要成果:
- 总共包括27名患者,5名患者经历过渡性脱.
- SJV 没有防止 ΔEELI 和 SpO2 从 T2- T3 降低 (p<0.001).
- 与WNJ (T1) 相比,SJV (T2) 的 ΔEELI 和 SpO2 (p<0. 001) 增加,腹肺通风率显著增加 (ROI Ventral: 43. 7% 至 60. 4%,p<0. 001).
结论:
- 在支气管检查过程中,尽管对肺呼吸有负面影响,但SJV保持了足够的SpO2.
- 与WNJ相比,bronchoscopy前的SJV改善了通风和氧化,但改变了通风向腹部区域的分布.
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