![Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F3777.jpg&w=3840&q=50)
感染和未感染的假体血管移植中的FDG-PET/CT
Sahar Alizada1, Zhou Lan2, Hina Shah3
1Department of Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
The international journal of cardiovascular imaging
|August 27, 2025
概括
氧葡萄糖正电子发射断层扫描/计算机断层扫描 (FDG-PET/CT) 有助于诊断假体血管移植感染 (PVGI). 特定的SUVmax和TBR吸收模式和值可以提高PVGI的诊断准确性.
科学领域:
- 核医学
- 放射学
- 传染性疾病
背景情况:
- 假体血管移植感染 (PVGI) 具有重大临床挑战,患病率和死亡率很高.
- 使用FDG-PET/CT区分受感染与非受感染的移植是复杂的,因为非受感染的移植会发生重叠的炎症.
- 需要改进诊断标准,以提高FDG-PET/CT用于PVGI检测的准确性.
研究的目的:
- 评估FDG-PET/CT在区分受感染和未受感染的假体血管移植中的诊断效用.
- 在诊断PVGI时确定FDG吸收强度和模式的最佳半定量值.
- 增强FDG-PET/CT用于PVGI诊断的临床应用.
主要方法:
- 对80名感染或未感染移植的患者进行了FDG-PET/CT后期分析.
- 评估FDG吸收强度 (视觉分级),模式 (焦点与扩散),标准化吸收值 (SUVmax) 和目标与背景比率 (TBR).
- 确定SUVmax和TBR的半定量值,以区分受感染和未受感染的移植.
主要成果:
- 在PVGI患者中观察到92. 6%的3级FDG吸收,而非感染患者中则为62. 3%.
- 与未感染的移植物相比,受感染的移植物 (66. 7%) 的焦点FDG吸收模式更为频繁.
- 在PVGI患者中,SUVmax和TBR的中位数显著上升. 一个SUVmax值为6. 2给出了70%的敏感性和79%的特异性,而一个TBR切断值为3. 3给出了PVGI的74%的敏感性和81%的特异性.
结论:
- FDG-PET/CT是诊断PVGI的一个有价值的工具,吸收强度和模式是关键指标.
- 确定SUVmax和TBR的半定量值可以帮助完善PVGI的诊断标准.
- 虽然FDG-PET/CT显示出有希望的结果,但谨慎的解释至关重要,以避免不必要的干预.
更多相关视频
17:13Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET
Published on: April 28, 2013
17.1K
10:04Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
18.9K
相关概念视频
01:13Radiological Investigation III: Pulmonary Angiogram and PET Scan
166
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
166
01:29Positron Emission Tomography
5.4K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
5.4K