婴儿早期神经发育在各种妊娠年龄范围内
Peggy H Y Chan1,2, C M Lai2, H S Lam1
1Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong SAR, China.
Journal of developmental and behavioral pediatrics : JDBP
|August 27, 2025
概括
怀孕年龄 (GA) 对婴儿发育有积极的影响. 每增加一周的GA会稍微提高认知,语言和运动技能,
科学领域:
- 神经科学
- 儿童发育医学
- 婴儿心理学
背景情况:
- 神经发育受到子宫内与子宫外环境的影响.
- 怀孕年龄 (GA) 是早产和早产婴儿大脑发育和神经发育结果的关键因素.
研究的目的:
- 综合研究各种妊娠年龄对认知,语言和运动发育的影响.
- 了解GA对婴儿各种发育领域的细微影响.
主要方法:
- 分析了454名在GA24至41周之间出生的婴儿.
- 使用贝利婴儿和幼儿发育量表 (Bayley Scales of Infant and Toddler Development,第三版 (Bayley-III)) 评估从8到30个月的儿童的认知,语言和运动发育.
- 应用线性和物流混合效应模型来分析GA和发育结果之间的关联.
主要成果:
- 怀孕年龄 (GA) 与所有评估的发育领域 (认知,语言,运动) 有着小但显著的积极关联.
- 每增加一周的GA与认知和语言得分的0. 6个点的增加以及贝利-III的运动得分的0. 62个点的增加相关.
- 在婴儿中,额外一周的GA可减少13%的接受性沟通延迟的几率.
结论:
- 怀孕年龄 (GA) 对广泛的认知,语言和运动发育有很小但可衡量的影响.
- 语言的发展,特别是接收性沟通, 似乎对早产的影响最敏感.
- 建议对早产和早产婴儿进行定期监测和以语言为重点的早期干预.
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