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Updated: Sep 10, 2025

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
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Published on: June 20, 2014

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含有库马林分子的希夫基衍生物的合成和抗真菌作用

Xin Zhang1, Hailing Fan1, Quanjia Chen2

  • 1College of Chemistry and Chemical Engineering, Xinjiang Agricultural University, 311 Nongda East Road, Urumqi 830052, China.

Journal of agricultural and food chemistry
|August 27, 2025
PubMed
概括

新合成的库马林希夫基对植物病原体具有强烈的抗真菌活性. 化合物3m在体外和体内表现出显著的疗效,作为新型真菌杀菌剂开发的糖酸脱酶抑制剂.

关键词:
在3D-QSAR抗真菌活性氨酸分子对接飞船基地

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The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the...
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In the presence of an aqueous base and a halogen, primary amides can lose the carbonyl (as carbon dioxide) and undergo rearrangement to form primary amines. This reaction, called the Hofmann rearrangement, can produce primary amines (aryl and alkyl) in high yields without contamination by secondary and tertiary amines.
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