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针对肝细胞中的FXR:增强纤维解和降低深静脉血栓的有希望的方法

Bolin Li1, Heze Fan1, Hao Wu2

  • 1The First Affiliated Hospital of Xi'an Jiaotong University, Xi'An, China.

Blood
|August 27, 2025
PubMed
概括

肥胖增加了深静脉血栓形成 (DVT) 的风险,因为血原激活剂抑制剂1 (PAI-1) 在肝脏中增加. 在肝细胞中激活FXR可降低PAI-1,改善纤维解和降低DVT负担.

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