在COVID-19后的世界,是否需要进行脑膜炎球菌B疫苗接种?
Amanda Izeli Portilho1, Elizabeth De Gaspari1
1Centro de Imunologia do Instituto Adolfo Lutz, São Paulo, SP, Brasil; Programa de Pós-Graduação Interunidades em Biotecnologia, Universidade de São Paulo, São Paulo, SP, Brasil.
Biomedica : revista del Instituto Nacional de Salud
|August 27, 2025
概括
由于疫苗接种缺口,由脑膜炎菌引起的脑膜炎球菌疾病仍然是一个全球性健康威胁,特别是B血清组. 呼吸系统病毒可能会增加对脑膜炎等细菌感染的易感性.
科学领域:
- 流行病学
- 传染性疾病
- 公共卫生
背景情况:
- 脑膜炎是全球细菌性脑膜炎的主要原因,通过呼吸道液滴传播.
- 脑膜炎由于高发病率,死亡率和流行病潜力而带来重大公共卫生挑战.
- 血清组B脑膜炎球菌感染面临着持续的挑战,在国家计划中的疫苗含量有限.
研究的目的:
- 提供关于脑膜炎球菌疾病的流行病学数据.
- 讨论导致预防细菌和病毒感染复杂性的因素.
主要方法:
- 对脑膜炎球菌病的流行病学数据的审查.
- 讨论有关病原体相互作用和预防的现有研究.
主要成果:
- 在COVID-19大流行期间观察到的持续性Neisseria脑膜炎血清组B感染.
- 流行后发现脑膜炎球菌病发病率增加.
- 有证据表明,呼吸道病毒可以增加对细菌呼吸道感染的易感性.
结论:
- 血清组B脑膜炎仍然是一个严重的公共卫生问题,需要改进预防策略.
- 病毒和细菌呼吸道感染之间的相互作用使预防工作复杂化.
- 需要进一步的研究来了解和解决影响细菌和病毒感染预防的复杂因素.
相关概念视频
Vaccinations
45.3K
Overview
45.3K
Microorganisms in Medicine and Therapeutics
312
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
312
Transmission-based Precautions II: Airborne and Protective Environment
1.5K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.5K
Immunological Memory
4.8K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
4.8K
Transmission-based Precautions I: Contact, Enteric, and Droplets
4.1K
Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
4.1K
Factors Affecting the Risk of Infection
12.3K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.3K


