多囊卵巢综合征中的碳水化合物数量与质量:基于人口的元分析与GBD数据驱动的评估
Yuxin Jin1, Li Zhang1, Xinwen Yu1
1Department of Endocrinology, Tangdu Hospital, The Fourth Military Medical University, Xi'an, 710038, Shaanxi Province, PR China.
Diabetes & metabolic syndrome
|August 27, 2025
概括
多囊卵巢综合症 (PCOS) 与低质量的碳水化合物有关,特别是更多的精制谷物和更少的全谷物和纤维. 不同的PCOS代谢表型可能需要个性化的饮食策略.
科学领域:
- 内分泌学
- 代谢疾病
- 营养科学
背景情况:
- 多囊卵巢综合征 (PCOS) 是一种普遍的代谢内分泌疾病.
- 目前关于碳水化合物摄入与PCOS之间联系的证据存在争议.
- 这项研究调查了碳水化合物数量和质量的对PCOS的影响.
研究的目的:
- 评估碳水化合物的数量和质量对多囊卵巢综合征 (PCOS) 的影响.
- 将全球流行病学数据与个人研究数据结合起来进行综合分析.
- 为了澄清碳水化合物摄入量与PCOS之间有争议的关系.
主要方法:
- 全球疾病负担分析 (GBD) 2021年PCOS发病率和饮食趋势的数据.
- 在6个数据库中进行系统的文献搜索,直到2025年2月为基于人口的研究.
- 对已确定的研究进行元分析,以评估PCOS和无PCOS妇女的碳水化合物摄入量差异.
主要成果:
- 全球数据显示,PCOS发病率上升与精制谷物和含糖饮料消费增加有关.
- 对25项研究 (n=20738) 的分析发现,总碳水化合物摄入量没有差异.
- 与对照组相比,患有PCOS的妇女的精制谷物摄入量显著增加,全谷物和纤维摄入量减少.
结论:
- 低质量的碳水化合物摄入量 (高精制谷物,低纤维/全谷物) 与PCOS的相关性比总碳水化合物量更强.
- 饮食模式,尤其是精制谷物消费,在PCOS中起着重要作用.
- 建议个性化饮食干预措施,考虑到PCOS中的多种代谢表型.
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