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Updated: May 10, 2026

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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结构保存的人类抗A35抗体保护小鼠和免受mopox病毒感染

Bin Ju1, Congcong Liu2, Jingjing Zhang3

  • 1Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong Province 518112, China; Guangdong Key Laboratory for Anti-infection Drug Quality Evaluation, Shenzhen, Guangdong Province 518112, China.

Cell
|August 27, 2025
PubMed
概括

两种人类单克隆抗体 (mAbs) 显示出对病毒 (mpox) 感染的保护. 结构分析揭示了这些抗A35 mAbs如何结合病毒,为新的抗病毒疗法和疫苗设计提供了洞察力.

关键词:
A35二次体动物模型抗体保护化电磁结构虫病毒在结构上保存的mAbs

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相关概念视频

Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...