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患有阿片类药物使用障碍的退伍军人住院后与死亡相关的因素

Michael A Incze1, Sophia Huebler2, Jacob D Baylis3

  • 1Division of General Internal Medicine, Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA; Program of Addiction Research, Clinical Care, Knowledge, and Advocacy (PARCKA), Division of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.

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概括

住院增加了阿片类药物使用障碍患者的死亡风险. 长时间停留等因素会增加死亡风险,而无家可归和布普伦诺芬治疗可能会降低死亡风险,指导未来的OUD治疗策略.

关键词:
排放计划与阿片类药物相关的疾病使用阿片类药物的疾病患者导航风险评估过渡期的护理

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科学领域:

  • 临床医学
  • 公共卫生
  • 上 精神病学

背景情况:

  • 患有阿片类药物使用障碍 (OUD) 的患者经常住院.
  • 虽然这些活动提供了参与的机会,但它们也带来了不稳定性,并与退院后的死亡率增加有关.
  • 识别风险因素对于改善过渡期护理至关重要.

研究的目的:

  • 在OUD的退伍军人中检查与医疗住院后死亡相关的患者级因素.
  • 区分与阿片类药物相关死亡率相关的因素.
  • 为开发风险分层工具和量身定制的干预提供信息.

主要方法:

  • 退伍军人卫生管理局 (VHA) 的回顾性队列研究.
  • 包括至少一次住院治疗的OUD退伍军人 (2011-2021年).
  • 分析了住院后30天和365天间临床/人口因素与死亡率之间的关联.

主要成果:

  • 年龄较大,医疗复杂性较高,多种物质使用障碍 (SUD) 和住院时间较长与全因死亡率的增加有关.
  • 无家可归,抑郁症,双相情感障碍,布普伦诺芬接收和服务连接与全因死亡率的降低有关.
  • 年龄较小,无家可归和多种SUD与阿片类药物相关的死亡率增加有关,而黑人种族和服务联系与阿片类药物相关的死亡率降低有关.

结论:

  • 在OUD的退伍军人中,患者层面的因素显著影响住院后的死亡风险.
  • 住院时间和并发症等因素影响全因死亡率,而特定的人口结构和治疗方式则影响与阿片类药物相关的死亡率.
  • 这些发现有助于制定针对性的干预措施和风险分层工具,以加强过渡期护理.