非最佳温度暴露可能损害心脏结构和功能:基于回声心脏成像的重复测量分析
Xingyi Qiu1, Yufei Cheng2, Qinglin He1
1School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and Key Lab of Health Technology Assessment of the Ministry of Health, Fudan University, Shanghai, 200032, China.
Environmental research
|August 27, 2025
概括
极端的环境温度,无论热或冷,都会对心脏结构和功能产生负面影响. 这项大型研究揭示了与温度相关的心脏参数的变化,影响持续长达10天.
科学领域:
- 心脏病学
- 环境健康
- 公共卫生
背景情况:
- 环境温度对心脏健康的影响尚未完全了解.
- 短期暴露于非最佳温度可能会影响心血管参数.
研究的目的:
- 研究短期环境温度暴露与心脏结构和功能之间的关系.
- 测量极端高温和低温对心血管健康的影响.
主要方法:
- 在中国上海对127,317名参与者的纵向研究 (2014-2020年) 进行了重复的心声图测试.
- 使用线性混合效应和分布式滞后非线性模型分析环境温度与心脏参数之间的关联.
- 检查了6个心脏结构和4个心脏功能参数.
主要成果:
- 在环境温度和大多数心脏参数之间观察到反向的U形关系.
- 温度对心脏参数的影响在5天内出现,持续约10天.
- 极低的 (1°C) 和高的 (33°C) 温度与肺动脉缩压的增加,S波峰值的改变,左心室喷射率的减少以及心脏结构参数的变化有关. 在年龄或性别分组之间没有显著差异.
结论:
- 极端的环境温度会对心脏结构和功能产生不利影响.
- 低温和高温都可能导致心脏重塑和心脏功能受损.
- 这些发现突显了与非最佳温度暴露相关的心血管风险.
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