与注意力缺陷多动症 (ADHD) 儿童的膀肠功能障碍 (BBD) 进行比较,并与ADHD医疗治疗的初始反应进行比较
Amy A Huang1, Christopher S Cooper1, Laura L Fuller2
1Department of Urology, University of Iowa, Iowa City, IA, 52242, USA.
患有注意力缺陷多动症 (ADHD) 和膀肠功能障碍 (BBD) 的儿童会出现更严重的症状. 虽然BBD治疗改善了非药物治疗的ADHD儿童的症状,但ADHD药物治疗状态影响了行为治疗的有效性.
科学领域:
- 儿童泌尿病学
- 神经发育障碍
- 行为健康
背景情况:
- 注意力缺陷多动症 (ADHD) 显著增加了儿童失禁的风险.
- 之前关于ADHD和膀肠道功能障碍 (BBD) 的研究主要集中在使用兴奋剂的儿童身上.
研究的目的:
- 为了比较ADHD儿童的BBD治疗效果, 区分服用和不服用ADHD药物的儿童.
- 与没有ADHD的儿童相比,建立BBD严重性的基线.
主要方法:
- 对5至18岁的尿道病患者进行了回顾性审查,诊断为BBD和ADHD.
- 使用儿科BBD问卷,并使用线性混合模型比较治疗反应.
- 包括泌尿疗法,肠道药物和抗胆固醇药物作为BBD治疗.
主要成果:
- 与没有ADHD的对照组相比,患有ADHD和BBD的患者的基线和最终BBD得分较高.
- 在仅接受泌尿疗法的组中,未服用ADHD药物的儿童的BBD得分显著更高.
- 当肠道和/或抗胆固醇药物添加到尿道治疗时,ADHD药物状态没有影响BBD得分或改善率.
结论:
- 伴随性ADHD在BBD的儿童中与BBD的严重程度增加有关,不论ADHD的药物治疗.
- 虽然BBD治疗对非药物治疗的儿童是有效的,但仅仅通过行为干预可以影响ADHD药物治疗的结果.
- 包括药物在内的联合疗法在ADHD儿童中显示出可比的BBD改善,无论药物状态如何.
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