中年和老年中国人的腹部肥胖与糖尿病之间的关联
Jiayi Hao1,2, Chunbian Tang1, Qingqing Yang3
1Medical School of Tianjin University, Tianjin, 300072, China.
Scientific reports
|August 27, 2025
概括
腹部肥胖症是低肌肉强度和腹部肥胖症的组合,可显著增加老年人糖尿病的风险. 腹部肥胖也会增加风险,而肌肉强度低却不会.
科学领域:
- 老年学
- 代谢健康
- 流行病学
背景情况:
- 糖尿病是一个日益严重的全球性健康问题,特别是在老年人群中.
- 之前的研究表明,肌肉强度低 (动力衰竭) 和腹部肥胖与糖尿病风险增加之间存在个别联系.
- 在中年和老年人中,肌和腹部肥胖对糖尿病风险的综合和协同影响仍未得到充分研究.
研究的目的:
- 调查动力衰竭和腹部肥胖与患糖尿病的风险的独立和联合关系.
- 确定腹部肥胖是否在老年人群中构成糖尿病的协同风险.
主要方法:
- 使用了2011-2020年中国健康与退休长度研究 (CHARLS) 的数据.
- 包括7934名45岁及以上的参与者.
- 通过手握强度和腰围测量来确定腹部肥胖症.
- 使用考克斯的比例危险模型来评估肌,腹部肥胖和糖尿病风险之间的关联,并进行了敏感性分析.
主要成果:
- 腹部肥胖与糖尿病的风险增加有显著的相关性 (HR=1.52).
- 仅腹部肥胖与糖尿病风险增加了54% (HR=1.54).
- 单独使用Dynapenia并没有增加糖尿病风险 (HR=1. 05).
结论:
- 腹部肥胖和腹部肥胖本身是中年和老年人患糖尿病的重要危险因素.
- 针对腹部肥胖症可能对老年人群的糖尿病预防至关重要,因为单独的动力衰竭似乎不是一个重要的独立风险因素.
相关概念视频
Diabetes: Symptoms, Diagnosis, and Complications
685
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
685
Psychoneuroimmunology: Diabetes and Cancer
62
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
62
Obesity
609
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
609
Diabetes Mellitus: Type 2 and Gestational
2.9K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.9K
Pathophysiology of Diabetes
1.2K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.2K
Carbohydrate Metabolism
11.7K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.7K


