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Updated: Sep 10, 2025

Identification of Homologous Recombination Events in Mouse Embryonic Stem Cells Using Southern Blotting and Polymerase Chain Reaction
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在中国血友病患者中使用长读序列和光学基因组映射识别F8复合重组

Yuxin Zhang1,2,3, Mingjie Yang4, Lulu Yan1,2,3

  • 1The Central Laboratory of Birth Defects Prevention and Control, The Affiliated Women and Children's Hospital of Ningbo University, Ningbo, China.

BMC medical genomics
|August 27, 2025
PubMed
概括

No abstract available in PubMed .

关键词:
一个F8基因复杂的结构变体血友病A长读数测序光学基因组图

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相关概念视频

Exon Recombination02:32

Exon Recombination

The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
Exon shuffling follows “splice frame rules.” Each exon...
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