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Updated: Sep 10, 2025

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空间转录学解码乳腺癌微环境异质性:从多维动态分析到精确治疗蓝图构建

Aolong Ma1, Lingyan Xiang1, Jingping Yuan1

  • 1Department of Pathology, Renmin Hospital of Wuhan University, Wuhan 430060, China.

Biomolecules
|August 28, 2025
PubMed
概括

空间转录学 (ST) 解码乳腺癌异质性和瘤微环境 (TME). 这项技术揭示了细胞相互作用并预测了治疗反应,为精确瘤学铺平了道路.

关键词:
乳腺癌不同质性疾病的进展和转移空间转录学治疗方法瘤微环境

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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